Novel  ERG11  and  TAC1b  Mutations Associated with Azole Resistance in Candida auris

descriptionPublicationkeyboard_double_arrow_right Article 19 Apr 2021 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 65 (issn: 0066-4804, eissn: 1098-6596,

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Authors: Jizhou Li; Alix T. Coste; Maroussia Liechti; Daniel Bachmann; Dominique Sanglard; Frederic Lamoth;

doi: 10.1128/aac.02663-20

pmid: 33619054

pmc: PMC8092887

Novel ERG11 and TAC1b Mutations Associated with Azole Resistance in Candida auris

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Abstract

Candida auris is a novel Candida species that has spread in all continents, causing nosocomial outbreaks of invasive candidiasis. C. auris has the ability to develop resistance to all antifungal drug classes. Notably, many C. auris isolates are resistant to the azole drug fluconazole, a standard therapy for invasive candidiasis.

Related Organizations

University Hospital of Lausanne
Switzerland
University of Lausanne
Switzerland
Institute of Microbiology
Switzerland

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