publication . Article . Other literature type . Preprint . 2020

The genetic architecture of the human cerebral cortex

Grasby, Katrina L; Jahanshad, Neda; Shatokhina, Natalia; Mirza-Schreiber, Nazanin; Moreira, Jose C V; Mühleisen, Thomas W; Müller-Myhsok, Bertram; Najt, Pablo; Nakahara, Soichiro; Nho, Kwangsik; ...
Open Access English
  • Published: 20 Mar 2020
Abstract
Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)—Genetics working group.
Subjects
Medical Subject Headings: endocrine system
free text keywords: Sciences bio-médicales et agricoles, Génétique moléculaire, General, [SDV]Life Sciences [q-bio], Article, /dk/atira/pure/subjectarea/asjc/1000, General, central sulcus, common variants, cortical sulci, expression, functional annotation, genome-wide association, loci, metaanalysis, observer-independent characterization, surface-area, Multidisciplinary, Cerebral cortex, medicine.anatomical_structure, medicine, Genetic architecture, Neuroscience, Biology, Genetic variation, Central sulcus, Genome-wide association study, Brain mapping, Attention deficit hyperactivity disorder, medicine.disease, Cortex (botany), ddc:320
Funded by
NIH| Multidisciplinary Schizophrenia Research Training
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 2T32MH067533-11A1
  • Funding stream: NATIONAL INSTITUTE OF MENTAL HEALTH
,
EC| TACTICS
Project
TACTICS
Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes
  • Funder: European Commission (EC)
  • Project Code: 278948
  • Funding stream: FP7 | SP1 | HEALTH
,
NIH| Neurogenetic Pathways to Drug Use in Young Adults
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 4R01DA033369-04
  • Funding stream: NATIONAL INSTITUTE ON DRUG ABUSE
,
NWO| How does the neural architecture of cognition map on its genetic architecture?
Project
  • Funder: Netherlands Organisation for Scientific Research (NWO) (NWO)
  • Project Code: 2300158588
,
NIH| Epidemiology of Venous Thrombosis &Pulmonary Embolism
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5R01HL059367-10
  • Funding stream: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Communities
NeuroinformaticsNI Projects
FET H2020FET FLAG: HBP FET Flagship core project
FET H2020FET FLAG: Human Brain Project Specific Grant Agreement 2

87 McClard, C. K. et al. POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain. The Journal of neuroscience : the official journal of the Society for Neuroscience 38, 1443-1461, doi:10.1523/jneurosci.1641-17.2017 (2018).

88 Dobson-Stone, C. et al. GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals. PloS one 8, e71750, doi:10.1371/journal.pone.0071750 (2013).

89 Arbogast, T. et al. Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition. PLoS genetics 13, e1006886, doi:10.1371/journal.pgen.1006886 (2017).

FOR2107: This work was funded by the German Research Foundation (DFG, grant FOR2107 DA1151/5-1 and DA1151/5-2 to UD; JA1890/7-1, JA1890/7-2 to AJ; KI 588/14-1, KI 588/14-2 to TK; KR 3822/7-1, KR 3822/7-2 to AK; NO246/10-1, NO246/10-2 to MMN).

Abstract
Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)—Genetics working group.
Subjects
Medical Subject Headings: endocrine system
free text keywords: Sciences bio-médicales et agricoles, Génétique moléculaire, General, [SDV]Life Sciences [q-bio], Article, /dk/atira/pure/subjectarea/asjc/1000, General, central sulcus, common variants, cortical sulci, expression, functional annotation, genome-wide association, loci, metaanalysis, observer-independent characterization, surface-area, Multidisciplinary, Cerebral cortex, medicine.anatomical_structure, medicine, Genetic architecture, Neuroscience, Biology, Genetic variation, Central sulcus, Genome-wide association study, Brain mapping, Attention deficit hyperactivity disorder, medicine.disease, Cortex (botany), ddc:320
Funded by
NIH| Multidisciplinary Schizophrenia Research Training
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 2T32MH067533-11A1
  • Funding stream: NATIONAL INSTITUTE OF MENTAL HEALTH
,
EC| TACTICS
Project
TACTICS
Translational Adolescent and Childhood Therapeutic Interventions in Compulsive Syndromes
  • Funder: European Commission (EC)
  • Project Code: 278948
  • Funding stream: FP7 | SP1 | HEALTH
,
NIH| Neurogenetic Pathways to Drug Use in Young Adults
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 4R01DA033369-04
  • Funding stream: NATIONAL INSTITUTE ON DRUG ABUSE
,
NWO| How does the neural architecture of cognition map on its genetic architecture?
Project
  • Funder: Netherlands Organisation for Scientific Research (NWO) (NWO)
  • Project Code: 2300158588
,
NIH| Epidemiology of Venous Thrombosis &Pulmonary Embolism
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5R01HL059367-10
  • Funding stream: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Communities
NeuroinformaticsNI Projects
FET H2020FET FLAG: HBP FET Flagship core project
FET H2020FET FLAG: Human Brain Project Specific Grant Agreement 2

87 McClard, C. K. et al. POU6f1 Mediates Neuropeptide-Dependent Plasticity in the Adult Brain. The Journal of neuroscience : the official journal of the Society for Neuroscience 38, 1443-1461, doi:10.1523/jneurosci.1641-17.2017 (2018).

88 Dobson-Stone, C. et al. GSK3B and MAPT polymorphisms are associated with grey matter and intracranial volume in healthy individuals. PloS one 8, e71750, doi:10.1371/journal.pone.0071750 (2013).

89 Arbogast, T. et al. Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition. PLoS genetics 13, e1006886, doi:10.1371/journal.pgen.1006886 (2017).

FOR2107: This work was funded by the German Research Foundation (DFG, grant FOR2107 DA1151/5-1 and DA1151/5-2 to UD; JA1890/7-1, JA1890/7-2 to AJ; KI 588/14-1, KI 588/14-2 to TK; KR 3822/7-1, KR 3822/7-2 to AK; NO246/10-1, NO246/10-2 to MMN).

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