G  M1  Ganglioside Treatment Facilitates Behavioral Recovery from Bilateral Brain Damage

descriptionPublicationkeyboard_double_arrow_right Article 20 Jul 1984 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science, volume 225, pages 340-342 (issn: 0036-8075, eissn: 1095-9203,

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Authors: B A, Sabel; M D, Slavin; D G, Stein;

doi: 10.1126/science.6740316

pmid: 6740316

G M1 Ganglioside Treatment Facilitates Behavioral Recovery from Bilateral Brain Damage

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Abstract

Adult rats with bilateral lesions of the caudate nucleus were treated with G M1 ganglioside. Although animals injected with a control solution were severely impaired in their ability to learn a complex spatial task, those treated with ganglioside were able to learn spatial reversals.

Related Organizations

University of Massachusetts System
United States
University of Massachusetts Amherst
United States
Clarke University
United States

Keywords

Male, Behavior, Animal, Rats, Inbred Strains, G(M1) Ganglioside, Rats, Brain Injuries, Gangliosides, Animals, Humans, Learning, Caudate Nucleus

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