A 69-year-old woman reported the appearance of a painful lump in the lower outer quadrant of right breast for 10 days. The patient had history of relapsing uveitis poorly responsive to therapy, thus she underwent high-dose steroid therapy for about 6 months. Clinical examination showed Cushing-like aspect of the patient, peripheral edema of inferior limbs, subcutaneous lumps in the right lumbar region, and distal third of forearm, which appeared some weeks before. Breast lump was especially painfulness with inflamed skin.