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Cardiovascular Dopamine Receptors: Role of Renal Dopamine and Dopamine Receptors in Sodium Excretion

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1990 English Publisher:WileyJournal:Pharmacology & Toxicology, volume 66, pages 237-243 (issn: 0901-9928,

Authors: Sharath S. Hegde; Mustafa F. Lokhandwala;

doi: 10.1111/j.1600-0773.1990.tb00741.x

pmid: 2196552

Cardiovascular Dopamine Receptors: Role of Renal Dopamine and Dopamine Receptors in Sodium Excretion

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Abstract

Research efforts in the area of peripheral dopamine have now established the presence of two distinct subtypes--DA1 and DA2--of DA receptors, and have identified a potential role for dopamine produced within the kidney in the control of renal sodium excretion. Selective DA1 and DA2 receptor agonists are being developed because they exhibit therapeutic potential for treatment of cardiovascular and renal disorders. Furthermore, basic research efforts are aimed towards identifying the stimulus and/or stimuli for the production of dopamine within the kidney and characterizing the cellular signalling processes involved in mediating the renal effects of dopamine and selective DA receptor agonists.

Related Organizations

University of Houston - Victoria
United States

Keywords

Dogs, Sodium, Animals, Humans, Kidney, Cardiovascular System, Rats, Receptors, Dopamine

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	48
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%