Summary.— Successful results are reported with hyperbaric oxygen treatment of 6 dermatological cases in which previous methods of therapy have been unsatisfactory. In one case of advanced generalized scleroderma, regression of the skin contraction was achieved, together with improved mobility of joints and healing of persistent ulcerations. In 2 cases of severe arterisoclerotic leg ulcers healing of healing of the ulcers was achieved without mutilating operations. In one case each of progressive pyoderma gangrenosum, ulcer of Felty's syndrome and fulminant bullous haemorrhagic erysipelas, full healing of the ulcers was also achieved. The nursing periods were undoubtedly greatly shortened, and the hyperbaric treatment could to a large extent be given on an ambulatory basis. No adverse side-effects were observed.