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European Journal of Neurology
Article . 2025 . Peer-reviewed
License: CC BY
Data sources: Crossref
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PubMed Central
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Cerebral Amyloid Angiopathy‐Related Inflammation in Iatrogenic Cerebral Amyloid Angiopathy

Authors: Larysa Panteleienko; Dermot Mallon; Cho Me Me Htet; Nathaniel Lizak; Michael Zandi; Gargi Banerjee; David J. Werring;

Cerebral Amyloid Angiopathy‐Related Inflammation in Iatrogenic Cerebral Amyloid Angiopathy

Abstract

ABSTRACTIntroductionCerebral amyloid angiopathy (CAA) related inflammation (CAA‐ri) is considered to be a distinct syndrome caused by an inflammatory response to amyloid‐β deposition in the walls of small leptomeningeal and cortical vessels in patients with sporadic CAA. However, recent data suggest that inflammation might contribute to a broader range of CAA subtypes.ResultsWe describe a case of probable iatrogenic CAA (iCAA), which manifested with multiple intracerebral haemorrhages complicated by the development of clinical and radiological features of CAA‐ri, which responded to steroids. Clinical, neuroimaging and CSF data suggested possible co‐existing Alzheimer's pathology.DiscussionCAA‐ri may occur in association with iCAA, suggesting that a broader spectrum of patients might benefit from steroid treatment than previously assumed.

Keywords

Inflammation, Male, Cerebral Amyloid Angiopathy, Iatrogenic Disease, Humans, Case Report, Female, Aged, Cerebral Hemorrhage

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
8
Top 10%
Average
Top 10%
Green
gold