publication . Article . Conference object . 2019

Ultra-High Frequencies continuous biological cell sorting based on repulsive and low dielectrophoresis forces

Thomas Provent; Remi Manczak; Sofiane Saada; Claire Dalmay; Barbara Bessette; Gaëlle Bégaud; Serge Battu; Pierre Blondy; M.O. Jauberteau; Fabrice Lalloué; ...
Open Access English
  • Published: 07 May 2019
  • Publisher: HAL CCSD
  • Country: France
Abstract
International audience; This paper demonstrates the superior capabilities of Ultra-High Frequency dielectrophoresis (UHF-DEP) to sort populations of biological cells based on their intracellular dielectric characteristics. The proposed concept combines both hydrofluidic and repulsive dielectrophoresis forces into a microfluidic lab-on-chip to create a UHF-DEP cytometer. The main objective is to sort different types of cells using only negative dielectrophoresis principle. The idea is to select proper frequency for the applied electric field in order to produce different intensity of repulsive DEP forces related to the cell type. This sorting principle, without p...
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Subjects
free text keywords: microfluidics, high frequencies, dielectrophoresis, biological cells, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Microfluidics, Cell sorting, Dielectrophoresis, sort, Sorting, Physics, Biological system, Electric field, Dielectric, Biological cell
Communities
  • FET H2020
Funded by
EC| SUMCASTEC
Project
SUMCASTEC
Semiconductor-based Ultrawideband Micromanipulation of CAncer STEm Cells
  • Funder: European Commission (EC)
  • Project Code: 737164
  • Funding stream: H2020 | RIA
Validated by funder
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