In this paper, successive cancellation of co-channel signals is described in the context of TDMA mobile radio systems employing coherent receivers. Both symbol aligned and misaligned co-channel signals are studied. Signal separability, which is a major problem in successive cancellation of co-channel signals, is obtained using the relative timing delay between co-channel signals. Both hard and soft subtractions are examined. Soft subtraction, where the estimated values are weighted with some reliability measure, leads to significant C/I gains for both coded and uncoded bits.