publication . Article . Part of book or chapter of book . Other literature type . 2012

Pulmonary Arterial Hypertension in Connective Tissue Diseases

Bruno Dino Bodini; Simona Sitia; Livio Tomasoni; Matteo Longhi; Maurizio Turiel;
Open Access English
  • Published: 30 Jun 2012 Journal: Allergology International, volume 60, issue 4, pages 405-409 (issn: 1323-8930, Copyright policy)
  • Publisher: Elsevier
Abstract
Pulmonary arterial hypertension (PAH) is a progressive disease caused by a remodeling of precapillary arterioles that leads to a progressive increase in pulmonary vascular resistance and right ventricular failure. PAH is associated with significant morbidity and mortality, despite the advent of specific therapies that target pathobiologic pathways implicated in the disease process [1–3]. PAH is can only be diagnosed by right heart catheterization (RHC) and is defined as a mean pulmonary artery pressure greater than 25 mmHg in the absence of elevation of the pulmonary capillary wedge pressure. PAH includes a heterogeneous group of clinical entities sharing simila...
Subjects
free text keywords: connective tissue diseases, corticosteroid, doppler echocardiography, mixed connective tissue disease, pulmonary hypertension, pulmonary arterial hypertension, systemic sclerosis, Cardiology and Cardiovascular Medicine, General Medicine, Pulmonary and Respiratory Medicine, Article, lcsh:Immunologic diseases. Allergy, lcsh:RC581-607, lcsh:Diseases of the musculoskeletal system, lcsh:RC925-935, Connective tissue disease, medicine.disease, medicine, Pathology, medicine.medical_specialty, Connective tissue, medicine.anatomical_structure, business.industry, business, Differential diagnosis, Poor prognosis, Central hemodynamics, Intensive care medicine, Pharmacotherapy, Dermatomyositis, Systemic lupus erythematosus, CTD, Pulmonary hypertension, Cardiology, Mixed connective tissue disease, Complication, Internal medicine, Polymyositis, Blood pressure, Doppler echocardiography, medicine.diagnostic_test, Cause of death, Surgery, Pulmonary wedge pressure, Heart failure, Vascular resistance, Pulmonary artery, medicine.artery, Portopulmonary hypertension

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