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Renal cell carcinoma

Authors: Jorge A, Garcia; C Lance, Cowey; Paul A, Godley;

Renal cell carcinoma

Abstract

This review is intended to provide information on recent advancements in renal cell carcinoma (RCC) treatments as well as give insight on present-day clinical and molecularly based biomarker studies.A review of recent literature regarding RCC epidemiology and clinical prognostic factors will be provided. Information from the latest molecularly based biomarker studies will be discussed. Finally, updates on recent additions to front-line therapy for RCC and the early clinical evidence examining the use of targeted agents sequentially or in combination will be given.Changes in the treatment paradigm of advanced RCC continue to evolve with additional novel agents in the horizon. This review will provide an update of the latest concepts in the epidemiology, molecularly based biomarker development and the management of patients with advanced RCC.

Keywords

Vascular Endothelial Growth Factor A, TOR Serine-Threonine Kinases, Antineoplastic Agents, Kidney Neoplasms, ErbB Receptors, Treatment Outcome, Biomarkers, Tumor, Disease Progression, Humans, Carcinoma, Renal Cell, Protein Kinases

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
38
Top 10%
Top 10%
Top 10%
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