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Australian and New Zealand Journal of Obstetrics and Gynaecology
Article . 2009 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
Obstetric Anesthesia Digest
Article . 2011 . Peer-reviewed
Data sources: Crossref
Obstetrical & Gynecological Survey
Article . 2010 . Peer-reviewed
Data sources: Crossref
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Castor Oil for Induction of Labor

Not Harmful, Not Helpful
Authors: Rose McGready; Rose McGready; Saw Oo Tan; Marcus J. Rijken; François Nosten; François Nosten; Mupawjay Pimanpanarak; +5 Authors

Castor Oil for Induction of Labor

Abstract

Background:  Castor oil is one of the most popular drugs for induction of labour in a non‐medical setting; however, published data on safety and effectiveness of this compound to induce labour remain sparse.Aim:  To assess the safety and effectiveness of castor oil for induction of labour in pregnancies with an ultrasound estimated gestational at birth of more than 40 weeks.Methods:  Data were extracted from hospital‐based records of all pregnant women who attended antenatal clinics on the Thai–Burmese border and who were more than 40 weeks pregnant. The effectiveness of castor oil to induce labour was expressed as time to birth and analysed with a Cox proportional hazards regression model. Measures associated with safety were fetal distress, meconium‐stained amniotic fluid, tachysystole of the uterus, uterine rupture, abnormal maternal blood pressure during labour, Apgar scores, neonatal resuscitation, stillbirth, post‐partum haemorrhage, severe diarrhoea and maternal death. Proportions were compared using Fisher's exact test.Results:  Of 612 women with a gestation of more than 40 weeks, 205 received castor oil for induction and 407 did not. The time to birth was not significantly different between the two groups (hazard ratio 0.99 (95% confidence interval: 0.81 to 1.20; n = 509)). Castor oil use was not associated with any harmful effects on the mother or fetus.Conclusions:  Castor oil for induction of labour had no effect on time to birth nor were there any harmful effects observed in this large series. Our findings leave no justification for recommending castor oil for this purpose.

Keywords

Adult, Castor Oil, Adolescent, Myanmar, Middle Aged, Thailand, Young Adult, Pregnancy, Oxytocics, Humans, Female, Labor, Induced, Proportional Hazards Models, Retrospective Studies

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    22
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
22
Top 10%
Top 10%
Average
Green