
pmid: 3453375
In this paper, we find the pressure waveform that minimizes the work of distending the alveoli in the lungs while achieving the desired mean airway pressure and alveolar tidal volume. The model used takes into account the compliance of the airway. The main result is a formula for the pressure waveform at the mouth as a function of time and lung parameters.
alveolar tidal volume, Respiration, Physiological, cellular and medical topics, Euler equations, Models, Biological, mean airway pressure, Pulmonary Alveoli, optimal control, pressure-limited ventilation, Pressure, Humans, pressure waveform, time and lung parameters, Mathematics
alveolar tidal volume, Respiration, Physiological, cellular and medical topics, Euler equations, Models, Biological, mean airway pressure, Pulmonary Alveoli, optimal control, pressure-limited ventilation, Pressure, Humans, pressure waveform, time and lung parameters, Mathematics
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