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Publication . Article . 2006

The interface between medically assisted reproduction and genetics: technical, social, ethical and legal issues*

Technical, social, ethical and legal issues
Sirpa Soini; Dolores Ibarreta; Violetta Anastasiadou; Ségolène Aymé; Suzanne Braga; Martina C. Cornel; Domenico A. Coviello; +11 Authors
Open Access  
Published: 15 Oct 2006 Journal: ESHRE Monographs, volume 2,006, pages 2-51 (issn: 1477-741X, eissn: 1477-8378, Copyright policy )
Publisher: Oxford University Press (OUP)
Country: Netherlands
The interface between assisted reproductive technologies (ART) and genetics comprises several sensitive and important issues that affect infertile couples, families with severe genetic diseases, potential children, professionals in ART and genetics, health care, researchers and the society in general. Genetic causes have a considerable involvement in infertility. Genetic conditions may also be transmitted to the offspring and hence create transgenerational infertility or other serious health problems. Several studies also suggest a slightly elevated risk of birth defects in children born following ART. PGD has become widely practiced throughout the world for various medical indications, but its limits are being debated. The attitudes towards ART and PGD vary substantially within Europe. The purpose of this article was to outline a framework for development of guidelines to be issued jointly by European Society of Human Genetics (ESHG) and European Society of Human Reproduction and Embryology (ESHRE) for the interface between genetics and ART. Technical, social, ethical and legal issues of ART and genetics will be reviewed.
Subjects by Vocabulary

Microsoft Academic Graph classification: Human genetics Assisted reproductive technology medicine.medical_treatment medicine Public health medicine.medical_specialty Genetics Reproductive technology Health care business.industry business Infertility medicine.disease Genetic counseling Human reproduction


Obstetrics and Gynecology, Reproductive Medicine

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