
Some nucleoporins, the nuclear pore complex (NPC) components, have exceptionally long lifetimes. In this issue, Toyama et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201809123) report that NPCs are maintained by a slow piecemeal replacement of NPC components in dividing and terminally differentiated cells and by whole-pore exchange in quiescent cells.
Cell Nucleus, Nuclear Pore Complex Proteins, Mosaicism, Commentaries, Nuclear Pore
Cell Nucleus, Nuclear Pore Complex Proteins, Mosaicism, Commentaries, Nuclear Pore
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