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Platelets and viruses

descriptionPublicationkeyboard_double_arrow_right Article 22 Feb 2021 English Publisher:Informa UK LimitedJournal:Platelets, volume 32, pages 325-330 (issn: 0953-7104, eissn: 1369-1635,

Authors: Silvio Antoniak; Nigel Mackman;

doi: 10.1080/09537104.2021.1887842

pmid: 33615982

pmc: PMC7987802

Platelets and viruses

- Summary
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Abstract

Platelets play an essential role in maintaining vascular integrity after injury. In addition, platelets contribute to the immune response to pathogens. For instance, they express receptors that mediate binding of viruses, and toll-like receptors that activate the cell in response to pathogen-associated molecular patterns. Platelets can be beneficial and/or detrimental during viral infections. They reduce blood-borne viruses by engulfing the free virus and presenting the virus to neutrophils. However, platelets can also enhance inflammation and tissue injury during viral infections. Here, we discuss the roles of platelets in viral infection.

Related Organizations

University of North Carolina at Chapel Hill
United States

Keywords

Blood Platelets, Neutrophils, coronavirus, Cell Communication, Viral Proteins, Animals, Humans, Diseases of the blood and blood-forming organs, Lymphocytes, Toll-Like Receptors, COVID-19, Dendritic Cells, Platelet Activation, Immunity, Innate, influenza a virus, Gene Expression Regulation, platelets, Host-Pathogen Interactions, Viruses, Receptors, Virus, myocarditis, RC633-647.5, Protein Binding

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	26
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%