publication . Article . 2005

Commonalities in Metabolism of Arsenicals

Blakely M. Adair; Stephen B. Waters; Vicenta Devesa; Zuzana Drobná; Miroslav Styblo; David J. Thomas;
Open Access
  • Published: 27 Sep 2005
Abstract
Environmental Context. Health effects associated with inorganic arsenic include various cancers and increased risk of diabetes. Millions of people in Bangladesh and India are at risk through use of contaminated drinking water. When humans ingest inorganic arsenic, it is rapidly converted to methylated metabolites. Although this methylation process is largely understood, the metabolism of other arsenicals (e.g. arsenosugars to dimethylarsenic) is very unclear. Connections among pathways for metabolism of various arsenicals are now being elucidated. Commonalities and differences in these pathways may be important determinants of the risk associated with exposure t...
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Medical Subject Headings: integumentary systeminorganic chemicals
free text keywords: Geochemistry and Petrology, Environmental Chemistry, Chemistry (miscellaneous), Biochemistry, Fluorescence spectrometry, Chemistry, Carcinogen, Increased risk, Metabolism, Xenobiotic, chemistry.chemical_compound, Inorganic arsenic, Arsenic, chemistry.chemical_element
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