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Biomaterials Science
Article . 2025 . Peer-reviewed
License: CC BY NC
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Crosslink strength governs yielding behavior in dynamically crosslinked hydrogels

Authors: Noah Eckman; Abigail K. Grosskopf; Grace Jiang; Krutarth Kamani; Michelle S. Huang; Brigitte Schmittlein; Sarah C. Heilshorn; +2 Authors

Crosslink strength governs yielding behavior in dynamically crosslinked hydrogels

Abstract

Injectable hydrogels have spawned great interest as vehicles for cell therapy. We find that crosslink strength controls the solid-to-liquid yielding transition; further, stronger crosslinks lead to brittle yielding, reducing injected cell viability.

Keywords

Cross-Linking Reagents, Hydrogels, Biocompatible Materials, Rheology

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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
hybrid