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Lab on a Chip
Article
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Europe PubMed Central
Other literature type . 2016
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Lab on a Chip
Article . 2016 . Peer-reviewed
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Controlled assembly of heterotypic cells in a core–shell scaffold: organ in a droplet

Authors: Qiushui Chen; Stefanie Utech; Dong Chen; Radivoje Prodanovic; Jin-Ming Lin; David A. Weitz;

Controlled assembly of heterotypic cells in a core–shell scaffold: organ in a droplet

Abstract

This paper reports a droplet-based microfluidic approach to fabricate a large number of monodisperse, portable microtissues, each in an individual drop. We use water-water-oil double emulsions as templates and spatially assemble hepatocytes in the core and fibroblasts in the shell, forming a 3D liver model in a drop.

Peer-reviewed manuscript: [http://cherry.chem.bg.ac.rs/handle/123456789/2820]

Supplementary material: [http://cherry.chem.bg.ac.rs/handle/123456789/3427]

Country
Serbia
Related Organizations
Subjects by Vocabulary

Microsoft Academic Graph classification: Scaffold Materials science Dispersity Microfluidics Nanotechnology Core shell Drop (liquid) Template

Keywords

Microfluidics, Biomedical Engineering, Bioengineering, Biochemistry, Article, Mice, Animals, Humans, Tissue Scaffolds, Water, Hydrogels, Hep G2 Cells, General Chemistry, NIH 3T3 Cells

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    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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download
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
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147
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Top 10%
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288
458
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