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Expanding the repertoire of pyrrolidyl PNA analogues for DNA/RNA hybridization selectivity: aminoethylpyrrolidinone PNA (aepone-PNA)

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2003 English Publisher:Royal Society of Chemistry (RSC)Journal:Chem. Commun. (issn: 1359-7345, eissn: 1364-548X, Copyright policy )
Authors: Nagendra K, Sharma; Krishna N, Ganesh;

doi: 10.1039/b307362a

pmid: 14587743

Expanding the repertoire of pyrrolidyl PNA analogues for DNA/RNA hybridization selectivity: aminoethylpyrrolidinone PNA (aepone-PNA)

Abstract

New PNA analogues derived from aminoethylpyrrolidin-5-one backbone show stabilization of aepone-PNA:DNA hybrids and destabilization of the corresponding RNA hybrids compared to unmodified PNA.

Related Organizations
Keywords

Models, Molecular, Peptide Nucleic Acids, Pyrrolidines, Models, Chemical, Molecular Structure, Temperature, Nucleic Acid Hybridization, RNA, DNA, Pyrrolidinones

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Average
Top 10%
Top 10%
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