
doi: 10.1038/ja.2008.29
pmid: 18503198
A new sulfoalkylresorcinol (1) was isolated from the marine-derived fungus, Zygosporium sp. KNC52. The structure of 1 was elucidated by spectroscopic methods including MS and NMR, and the absolute stereochemistry was determined by the modified Mosher's method. Compound 1 inhibited FtsZ polymerization in vitro and exhibited weak antimicrobial activity against multi-drug-resistant bacteria.
Magnetic Resonance Spectroscopy, Bacteria, Fungi, Molecular Conformation, Microbial Sensitivity Tests, Resorcinols, Spectrometry, Mass, Fast Atom Bombardment, Cytoskeletal Proteins, Bacterial Proteins, Indicators and Reagents
Magnetic Resonance Spectroscopy, Bacteria, Fungi, Molecular Conformation, Microbial Sensitivity Tests, Resorcinols, Spectrometry, Mass, Fast Atom Bombardment, Cytoskeletal Proteins, Bacterial Proteins, Indicators and Reagents
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