Possible leap ahead in filovirus therapeutics

descriptionPublicationkeyboard_double_arrow_right Article 15 Apr 2014 English Publisher:Springer Science and Business Media LLCJournal:Cell Research, volume 24, pages 647-648 (issn: 1001-0602, eissn: 1748-7838,

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Authors: Darryl, Falzarano; Heinz, Feldmann;

doi: 10.1038/cr.2014.49

pmid: 24732011

pmc: PMC4042172

Possible leap ahead in filovirus therapeutics

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Abstract

In a recent study published in Nature, Warren et al. describe the generation of a novel synthetic adenosine analogue, BCX4430, a synthetic drug-like small molecule that provides protection from Ebola and Marburg virus infection in animal models.

Related Organizations

National Institute of Allergy and Infectious Diseases
United States
National Institutes of Health
United States
National Heart, Lung, and Blood Institute Division of Intramural Research
United States
National Institute of Health
Pakistan

Keywords

Adenosine, Filoviridae Infections, Animals, Humans, Purine Nucleosides, Filoviridae, Antiviral Agents

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