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Cell Research
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Cell Research
Article . 2014 . Peer-reviewed
License: Springer TDM
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Cell Research
Article . 2015
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https://dx.doi.org/10.1038/cr....
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FTO: linking m6A demethylation to adipogenesis

descriptionPublicationkeyboard_double_arrow_right Article 05 Dec 2014 English Publisher:Springer Science and Business Media LLCJournal:Cell Research, volume 25, pages 3-4 (issn: 1001-0602, eissn: 1748-7838, Copyright policy )
Authors: Moshe Shay, Ben-Haim; Sharon, Moshitch-Moshkovitz; Gideon, Rechavi;

doi: 10.1038/cr.2014.162

pmid: 25475057

pmc: PMC4650590

FTO: linking m6A demethylation to adipogenesis

Abstract

Polymorphism of the FTO gene encoding an N(6)-methyladenosine (m(6)A) RNA demethylase was robustly associated with human obesity; however, the mechanism by which FTO affects metabolism, considering its emerging role in RNA modification, is still poorly understood. A new study published in Cell Research reports novel functions implicating FTO in the regulation of mRNA alternative splicing in the control of adipogenesis.

Related Organizations
Keywords

Adenosine, Adipogenesis, RNA Splicing, Adipocytes, Animals, Oxo-Acid-Lyases, RNA, Messenger, Mixed Function Oxygenases

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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
100
Top 1%
Top 10%
Top 10%
bronze
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