Principles of CDK regulation

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1995 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 374, pages 131-134 (issn: 0028-0836, eissn: 1476-4687,

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Authors: D O, Morgan;

doi: 10.1038/374131a0

pmid: 7877684

Principles of CDK regulation

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Abstract

As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.

Related Organizations

University of California, San Francisco
United States

Keywords

Cyclins, Cell Cycle, Animals, Phosphorylation, Catalysis, Cyclin-Dependent Kinases

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