Synergistic Action of HL-A Isoantibodies

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1969 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 222, pages 94-95 (issn: 0028-0836, eissn: 1476-4687,

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Authors: A, Svejgaard;

doi: 10.1038/222094a0

pmid: 5775841

Synergistic Action of HL-A Isoantibodies

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Abstract

HUMAN HL-A transplantation antigens are controlled by a large number of closely linked genes1. So far only dominant HL-A genes have been described, but some of the sera containing complement fixing (C′F) platelet isoantibodies used for HL-A typing in this laboratory occasionally react as if they were active against antigens controlled by recessive genes or genes with incomplete penetrance.

Related Organizations

Aarhus University Hospital
Denmark

Keywords

Antigen-Antibody Reactions, Blood Platelets, Italy, Isoantibodies, Denmark, Genetics, Medical, Histocompatibility Testing, Blood Group Antigens, Humans, Genes, Recessive, Lymphocytes, Hemolysis

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