Determination of Oenothein B as the Active 5-α-Reductase-Inhibiting Principle of the Folk Medicine Epilobium parviflorum
Copyright policy )Determination of Oenothein B as the Active 5-α-Reductase-Inhibiting Principle of the Folk Medicine Epilobium parviflorum
Several extracts from Epilobium parviflorum, a plant used in Central Europe for the treatment of prostate disorders, were evaluated in a biochemical assay with 5-alpha-reductase. The aqueous extract displaying inhibition of the enzyme was analyzed, the fraction responsible for this activity was purified, and the active compound identified as a macrocyclic tannin, oenothein B (1).
- Roussel Uclaf France
Male, Plants, Medicinal, Prostate, In Vitro Techniques, Hydrolyzable Tannins, 5-alpha Reductase Inhibitors, Austria, Humans, Spectrophotometry, Ultraviolet, Enzyme Inhibitors, Tannins, Chromatography, High Pressure Liquid
Male, Plants, Medicinal, Prostate, In Vitro Techniques, Hydrolyzable Tannins, 5-alpha Reductase Inhibitors, Austria, Humans, Spectrophotometry, Ultraviolet, Enzyme Inhibitors, Tannins, Chromatography, High Pressure Liquid
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