Bisphenol-A (BPA), BPA Glucuronide, and BPA Sulfate in Midgestation Umbilical Cord Serum in a Northern and Central California Population
Copyright policy )Bisphenol-A (BPA), BPA Glucuronide, and BPA Sulfate in Midgestation Umbilical Cord Serum in a Northern and Central California Population
Bisphenol-A (BPA) is an endocrine disrupting chemical used in numerous consumer products, resulting in universal exposure in the United States. Prenatal exposure to BPA is associated with numerous reproductive and developmental effects in animals. However, little is known about human fetal exposure or metabolism of BPA during midgestation. In the present study, we present a new liquid chromatography-tandem mass spectrometry method to directly measure concentrations of BPA and two predominant metabolic conjugates-BPA glucuronide and BPA sulfate-in umbilical cord serum collected from elective second trimester pregnancy terminations. We detected at least one form of BPA in all umbilical cord serum samples: BPA (GM 0.16, range
- University of California, San Francisco United States
- Washington State University United States
- Washington State University United States
Adult, Male, Adolescent, 610, Reproductive health and childbirth, Sulfuric Acid Esters, Toxicology, Medical sciences, California, Mass Spectrometry, Umbilical Cord, Young Adult, Fetus, Glucuronides, Phenols, Pregnancy, Animals, Humans, Benzhydryl Compounds, Biological and medical sciences, Pediatric, Chromatography, Liquid, Biomedical and Clinical Sciences, Reproducibility of Results, Perinatal Period - Conditions Originating in Perinatal Period, Middle Aged, Reference Standards, Various organic compounds, Chemical and industrial products toxicology. Toxic occupational diseases, Good Health and Well Being, Reproductive Medicine, Environmental Pollutants, Female, Environmental Sciences, Chromatography, Liquid
Adult, Male, Adolescent, 610, Reproductive health and childbirth, Sulfuric Acid Esters, Toxicology, Medical sciences, California, Mass Spectrometry, Umbilical Cord, Young Adult, Fetus, Glucuronides, Phenols, Pregnancy, Animals, Humans, Benzhydryl Compounds, Biological and medical sciences, Pediatric, Chromatography, Liquid, Biomedical and Clinical Sciences, Reproducibility of Results, Perinatal Period - Conditions Originating in Perinatal Period, Middle Aged, Reference Standards, Various organic compounds, Chemical and industrial products toxicology. Toxic occupational diseases, Good Health and Well Being, Reproductive Medicine, Environmental Pollutants, Female, Environmental Sciences, Chromatography, Liquid
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