publication . Article . 2006

Evolutionary genomics of nucleo-cytoplasmic large DNA viruses

Lakshminarayan M. Iyer; S. Balaji; Eugene V. Koonin; L. Aravind;
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  • Published: 22 Feb 2006 Journal: Virus Research, volume 117, pages 156-184 (issn: 0168-1702, Copyright policy)
  • Publisher: Elsevier BV
A previous comparative-genomic study of large nuclear and cytoplasmic DNA viruses (NCLDVs) of eukaryotes revealed the monophyletic origin of four viral families: poxviruses, asfarviruses, iridoviruses, and phycodnaviruses [Iyer, L.M., Aravind, L., Koonin, E.V., 2001. Common origin of four diverse families of large eukaryotic DNA viruses. J. Virol. 75 (23), 11720-11734]. Here we update this analysis by including the recently sequenced giant genome of the mimiviruses and several additional genomes of iridoviruses, phycodnaviruses, and poxviruses. The parsimonious reconstruction of the gene complement of the ancestral NCLDV shows that it was a complex virus with at...
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free text keywords: Cancer Research, Infectious Diseases, Virology, Marseilleviridae, biology.organism_classification, biology, Virophage, Megavirus, Megaviridae, Giant Virus, Genetics, Nucleocytoplasmic large DNA viruses, Mimivirus, Pandoravirus
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Article . 2006
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Article . 2006
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