Name: Discovering Antimalarials
Creator: Timothy J. Egan
Keywords: Pharmacology, 0301 basic medicine, Clinical Biochemistry, Plasmodium falciparum, Protozoan Proteins, Proteins, Biochemistry, 3. Good health, Antimalarials, 03 medical and health sciences

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2002 English Publisher:Elsevier BVJournal:Chemistry & Biology, volume 9, pages 852-853 (issn: 1074-5521,

Authors: Timothy J. Egan;

doi: 10.1016/s1074-5521(02)00196-5

pmid: 12204682

Discovering Antimalarials

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Abstract

Recent discoveries have uncovered some key processes that occur in the food vacuole of the malarial parasite. Consequently, new families of potential antimalarials that inhibit HRP-2, a hitherto unexplored drug target, were identified using a novel screening method.

Related Organizations

University of Cape Town
South Africa

Keywords

Pharmacology, Clinical Biochemistry, Plasmodium falciparum, Protozoan Proteins, Proteins, Biochemistry, Antimalarials, Histidine-Rich Glycoprotein, Drug Design, Drug Discovery, Molecular Medicine, Animals, Humans, Molecular Biology

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