Eukaryotic transcription factors
Copyright policy )Eukaryotic transcription factors
The structural characterization of eukaryotic transcription factors that interact with DNA has advanced on two fronts in the past two years. New complexes of transcription factors bound to TATA-box DNA include the TFIIA-TBP-DNA complex as well as human and archaeal TBP-DNA and TFIIB-TBP-DNA complexes, respectively. In addition, recent studies of proximal/distal promoter complexes demonstrate that DNA-binding motifs may be modified in nature by adding secondary structure elements to diversify DNA-binding specificities and affinities.
- Institute of Molecular Biology and Biophysics Switzerland
- ETH Zurich Switzerland
Models, Molecular, Protein Conformation, Helix-Loop-Helix Motifs, Zinc Fingers, Archaea, TATA Box, DNA-Binding Proteins, Animals, Humans, Nucleic Acid Conformation, Dimerization, Helix-Turn-Helix Motifs, Transcription Factors
Models, Molecular, Protein Conformation, Helix-Loop-Helix Motifs, Zinc Fingers, Archaea, TATA Box, DNA-Binding Proteins, Animals, Humans, Nucleic Acid Conformation, Dimerization, Helix-Turn-Helix Motifs, Transcription Factors
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