
pmid: 12581657
Recent structural and biophysical results have provided unprecedented insights into the structure and function of the bacterial RNA polymerase holoenzyme as it goes through the steps of transcription initiation. Comparisons with structural analyses of evolutionarily unrelated RNA polymerases reveal unexpected general features of the initiation process.
Models, Molecular, Binding Sites, Crystallography, Bacteria, Macromolecular Substances, Protein Conformation, Sigma Factor, DNA, DNA-Directed RNA Polymerases, Protein Structure, Tertiary, Bacterial Proteins, RNA, Thermus, Holoenzymes, Promoter Regions, Genetic, Protein Binding
Models, Molecular, Binding Sites, Crystallography, Bacteria, Macromolecular Substances, Protein Conformation, Sigma Factor, DNA, DNA-Directed RNA Polymerases, Protein Structure, Tertiary, Bacterial Proteins, RNA, Thermus, Holoenzymes, Promoter Regions, Genetic, Protein Binding
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