Name: Presynaptic induction and expression of NMDA-dependent LTP
Creator: Denis Paré
Keywords: 0301 basic medicine, 0303 health sciences, N-Methylaspartate, Long-Term Potentiation, Amygdala, Hippocampus, Synaptic Transmission, 3. Good health, 03 medical and health sciences, Memory

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2004 English Publisher:Elsevier BVJournal:Trends in Neurosciences, volume 27, pages 440-441 (issn: 0166-2236,

Authors: Denis Paré;

doi: 10.1016/j.tins.2004.05.004

pmid: 15271488

Presynaptic induction and expression of NMDA-dependent LTP

- Summary
- Subjects
- Metrics

Abstract

It is almost axiomatic in neuroscience that postsynaptically induced NMDA-dependent long-term potentiation (LTP) is a cellular substrate of memory. As a result, memory impairments caused by experimental reductions of NMDA currents are often interpreted as evidence that this form of plasticity is involved in memory formation. However, a recent Nature study indicates that not all NMDA-dependent LTP is induced postsynaptically.

Related Organizations

Rutgers, The State University of New Jersey
United States

Keywords

N-Methylaspartate, Long-Term Potentiation, Amygdala, Hippocampus, Synaptic Transmission, Memory, Synapses, Animals, Humans, Nerve Net

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	21
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%