Asymmetric synthesis of chiral spiro bis(isoxazoline) and spiro (isoxazole–isoxazoline) ligands

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2010 English Publisher:Elsevier BVJournal:Tetrahedron: Asymmetry, volume 21, pages 379-381 (issn: 0957-4166,

Authors: Toyohiro Nagano; Hiroaki Sasai; Kazuhiro Takenaka; Shinobu Takizawa;

doi: 10.1016/j.tetasy.2010.03.006

Asymmetric synthesis of chiral spiro bis(isoxazoline) and spiro (isoxazole–isoxazoline) ligands

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Abstract

Abstract Asymmetric synthesis of novel chiral ligands, bis(isoxazoline) on a spiro[4.4]nonane scaffold and isoxazole–isoxazoline on a spiro[4.5]decane scaffold, has been achieved by utilizing an enantiomerically pure alcohol as the starting material.

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Osaka University
Japan

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CCDC 745562: Experimental Crystal Structure Determination
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CCDC 745563: Experimental Crystal Structure Determination
2010IsSupplementedBy

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