When Fibroblasts MET iPSCs

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 2010 English Publisher:Elsevier BVJournal:Cell Stem Cell, volume 7, pages 5-6 (issn: 1934-5909,

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Authors: Polo, Jose M.; Hochedlinger, Konrad;

doi: 10.1016/j.stem.2010.05.018

pmid: 20621040

When Fibroblasts MET iPSCs

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Abstract

Two independent studies by Li et al. (2010) and Samavarchi-Tehrani et al. (2010) in this issue of Cell Stem Cell suggest that a mesenchymal-to-epithelial transition is a critical initiating event during the derivation of induced pluripotent stem cells (iPSCs) from fibroblasts, indicating remarkable similarities between cellular reprogramming, development, and cancer.

Related Organizations

Howard Hughes Medical Institute
United States
Massachusetts General Hospital
United States
Harvard University
United States
Harvard Stem Cell Institute, Cambridge, MA, USA
United States

Keywords

Genetics, Molecular Medicine, Cell Biology

1 Research products, page 1 of 1

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts
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