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Microvascular Research
Article . 2008 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
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Nerve growth factor as an angiogenic factor

Authors: BENAGIANO V; CRIVELLATO, Enrico; MANGIERI D; NICO B; RIBATTI D.;

Nerve growth factor as an angiogenic factor

Abstract

Nerve growth factor (NGF), a neurotrophin that plays a crucial role in promoting neurotrophic and neurotropic effects in sympathetic neurons, has recently been identified as a novel angiogenic molecule, which exerts a variety of effects in the cardiovascular system and on endothelial cells. In fact, NGF may contribute to maintenance, survival, and function of endothelial cells by autocrine and/or paracrine mechanisms. This review summarizes the involvement of NGF in the regulation of angiogenesis in both normal and pathological conditions.

Keywords

Vascular Endothelial Growth Factor A, Wound healing, Neovascularization, Physiologic, Biochemistry, Nerve growth factor, Ischemia, Neoplasms, Nerve Growth Factor, Animals, Humans, Angiogenic Proteins, Physiologic, Tumor growth, Neovascularization, Cell Proliferation, Pathologic, Angiogenic Protein, Endothelial Cell, Wound Healing, Neovascularization, Pathologic, Animal, Endothelial Cells, Angiogenesi, Neoplasm, Cardiology and Cardiovascular Medicine, Human, Signal Transduction

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    169
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
169
Top 10%
Top 10%
Top 1%
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