Reverse Transcribing the Code for Chromosome Stability

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 2009 English Publisher:Elsevier BVJournal:Molecular Cell, volume 36, pages 715-719 (issn: 1097-2765,

Copyright policy )

Authors: Artandi, Steven E.; Cooper, Julia Promisel;

doi: 10.1016/j.molcel.2009.11.030

pmid: 20005831

Reverse Transcribing the Code for Chromosome Stability

- Summary
- Subjects
- Metrics

Abstract

The linearity of eukaryotic chromosomes presents challenges to cells, as the presence of DNA "ends" poses problems for the DNA replication machinery and the cell's damage response systems. This year's Nobel Prize in Physiology or Medicine recognized groundbreaking studies establishing the telomere field as a crucial area of biomedical research.

Related Organizations

Cancer Research UK
United Kingdom
London Research Institute
United Kingdom
Stanford University
United States

Keywords

DNA Replication, Models, Genetic, Mitosis, Cell Biology, History, 20th Century, Telomere, Nobel Prize, Chromosomal Instability, Genetics, Humans, Molecular Biology, Telomerase

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	12
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average