Telomere and adaptive immunity
Copyright policy )Telomere and adaptive immunity
The adaptive immune response relies on the ability of lymphocytes to undergo periodic massive expansion. It is an enigma how lymphocytes are able to undergo this seemingly unlimited number of cell divisions. Telomeres and telomerase play a critical role in regulation of the replicative lifespan of cells, providing a potential mechanism which lymphocytes may employ. Here I will review the recent progress of the role of telomeres and telomerase in lymphocyte differentiation, function, and aging.
- National Institutes of Health United States
- National Institute on Aging United States
- National Institute of Health Pakistan
B-Lymphocytes, Immunity, Cellular, T-Lymphocytes, Cell Differentiation, Telomere, Dyskeratosis Congenita, Oxidative Stress, Humans, Telomerase, Cellular Senescence
B-Lymphocytes, Immunity, Cellular, T-Lymphocytes, Cell Differentiation, Telomere, Dyskeratosis Congenita, Oxidative Stress, Humans, Telomerase, Cellular Senescence
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