Sterols in asthma

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2022 English Publisher:Elsevier BVJournal:Trends in Immunology, volume 43, pages 792-799 (issn: 1471-4906,

Copyright policy )Funded by:NIH | Epigenetic modulation of ..., NIH | Novel knockout models to ..., NIH | Novel Epigenetic Modifier... +2 projects

Authors: Mireia Guerau-de-Arellano; Rodney D. Britt;

doi: 10.1016/j.it.2022.08.003

pmid: 36041950

pmc: PMC9513744

Sterols in asthma

- Summary
- Subjects
- Metrics

Abstract

While sterols regulate immune processes key to the pathogenesis of asthma, inhibition of sterols with statin drugs has shown conflicting results in human asthma. Here, a novel understanding of the impact of sterols on type 17 immune responses and asthma lead us to hypothesize that sterols and statins may be relevant to severe asthma endotypes with neutrophil infiltration.

Related Organizations

OHIO STATE UNIVERSITY
Institute for Behavioral Medicine
United States
The Ohio State University
United States
The Ohio State University
United States
THE OHIO STATE UNIVERSITY
United States

Keywords

Sterols, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Asthma

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	7
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%