IL-33 Deals with the Gray Matter

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 2018 English Publisher:Elsevier BVJournal:Immunity, volume 48, pages 484-486 (issn: 1074-7613,

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Authors: Charlène, Delmas; Elise, Dalmas;

doi: 10.1016/j.immuni.2018.03.005

pmid: 29562200

IL-33 Deals with the Gray Matter

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Abstract

The central nervous system undergoes extensive postnatal synapse remodeling that is critical for the formation of mature neural circuits. In a recent issue of Science, Vainchtein et al. (2018) describe an additional role for astrocyte-derived interleukin-33 (IL-33) in promoting synapse refinement by microglia in the developing brain.

Related Organizations

Inserm
France
Sorbonne
France
French Institute of Health and Medical Research
France
University of Paris
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Paris Diderot University
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Keywords

Neurogenesis, Brain, Interleukin-33, Astrocytes, Synapses, Animals, Humans, Microglia, Gray Matter

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