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Immunity
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Immunity
Article . 2015
License: Elsevier Non-Commercial
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Natural Killer Cell Memory

Authors: O’Sullivan, Timothy E; Sun, Joseph C; Lanier, Lewis L;

Natural Killer Cell Memory

Abstract

Natural killer (NK) cells have historically been considered short-lived cytolytic cells that can rapidly respond against pathogens and tumors in an antigen-independent manner and then undergo cell death. Recently, however, NK cells have been shown to possess traits of adaptive immunity and can acquire immunological memory in a manner similar to that of T and B cells. In this review, we discuss evidence of NK cell memory and the mechanisms involved in the generation and survival of these innate lymphocytes.

Country
United States
Keywords

Dermatitis, Apoptosis, Adaptive Immunity, CD8-Positive T-Lymphocytes, Dermatitis, Contact, Lymphocyte Activation, Peyer's Patches, Mice, Models, Contact, Receptors, 2.1 Biological and endogenous factors, Killer Cells, Immunology and Allergy, Homeostasis, Viral, Lymphocytes, Antigens, Viral, natural killer cells, Adoptive Transfer, Killer Cells, Natural, Immunological, Infectious Diseases, Virus Diseases, Natural, HIV/AIDS, Cytokines, Immunotherapy, 570, 1.1 Normal biological development and functioning, Immunology, 610, immunological memory, Biodefense, Animals, Humans, Antigens, cytomegalovirus, Homeodomain Proteins, Inflammation, Biomedical and Clinical Sciences, Inflammatory and immune system, Models, Immunological, Lymphocyte Subsets, Emerging Infectious Diseases, Sexually Transmitted Infections, Natural Killer Cell, Haptens, Immunologic Memory

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    297
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
297
Top 1%
Top 10%
Top 1%
Green
hybrid