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Mitotic Spindle: Illuminating Spindle Positioning with a Biological Lightsaber

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 2018 India Publisher:Elsevier BVJournal:Current Biology, volume 28, pages R1308-R1310 (issn: 0960-9822, Copyright policy )
Authors: Kotak, Sachin;

doi: 10.1016/j.cub.2018.09.047

pmid: 30458151

Mitotic Spindle: Illuminating Spindle Positioning with a Biological Lightsaber

Abstract

In metazoans, positioning of the mitotic spindle is controlled by the microtubule-dependent motor protein dynein, which associates with the cell cortex. Using optogenetic tools, two new studies examine how the levels and activity of dynein are regulated at the cortex to ensure proper positioning of the mitotic spindle.

Country
India
Related Organizations
Keywords

Microbiology & Cell Biology, Dyneins, Kinesins, Dynactin Complex, Spindle Apparatus, Microtubules

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 74
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
74
Top 1%
Top 10%
Top 10%
hybrid