Recent in vivo and in vitro studies have challenged existing models of olfactory processing in the vertebrate olfactory bulb and insect antennal lobe. Whereas lateral connectivity between olfactory glomeruli was previously thought to form a dense, topographically organized inhibitory surround, new evidence suggests that lateral connections may be sparse, nontopographic, and partly excitatory. Other recent studies highlight the role of active sensing (sniffing) in shaping odor-evoked neural activity and perception.