
ResumenAntecedentesLos tumores del estroma gastrointestinal (GIST) son los sarcomas más comunes del tracto digestivo. Las localizaciones más frecuentes son estómago (60-70%) e intestino delgado (25-30%).Los síntomas más comunes son hemorragia de tubo digestivo, dolor abdominal, tumor abdominal y obstrucción intestinal. Estos dependen de la localización y del tamaño del tumor. El diagnóstico es histológico. El 95% de los GIST son positivos para CD117.Casos clínicosEstudio observacional y descriptivo en el que se reportan 5 casos de GIST de yeyuno e íleon, que tuvieron como manifestación clínica principal hemorragia de tubo digestivo de origen oscuro. El periodo de tiempo al diagnóstico varió de 1 a 84 meses. La endoscopia, en todos los pacientes, no fue concluyente y el diagnóstico se hizo por angiotomografía abdominal. El tratamiento incluyó, en todos los casos, resección.ConclusionesLos GIST pueden tener formas de presentación y síntomas inusuales como la hemorragia de origen oscuro. La tomografía con medio de contraste y la angiografía son herramientas que han demostrado ser útiles para el diagnóstico certero de este tipo de lesiones.AbstractBackgroundThe gastrointestinal stromal tumours (GIST) are the most common soft tissue sarcomas of the digestive tract. They are usually found in the stomach (60-70%) and small intestine (25-30%) and, less commonly, in the oesophagus, mesentery, colon, or rectum.The symptoms present at diagnosis are, gastrointestinal bleeding, abdominal pain, abdominal mass, or intestinal obstruction. The type of symptomatology will depend on the location and size of the tumour. The definitive diagnosis is histopathological, with 95% of the tumours being positive for CD117.Clinical casesThis is an observational and descriptive study of 5cases of small intestinal GIST that presented with gastrointestinal bleeding as the main symptom. The period from the initial symptom to the diagnosis varied from 1 to 84 months. The endoscopy was inconclusive in all of the patients, and the diagnosis was made using computed tomography and angiography. Treatment included resection in all patients. The histopathological results are also described.ConclusionGIST can have multiple clinical pictures and unusual symptoms, such as obscure gastrointestinal bleeding. The use of computed tomography and angiography has shown to be an important tool in the diagnosis with patients with small intestine GISTs.
Medicine(all), Obscure gastrointestinal bleeding, Jejunum, Tumor de estroma gastrointestinal, Intestino delgado, Small intestine, Gastrointestinal stromal tumor, Yeyuno, Sangrado de tubo digestivo de origen oscuro
Medicine(all), Obscure gastrointestinal bleeding, Jejunum, Tumor de estroma gastrointestinal, Intestino delgado, Small intestine, Gastrointestinal stromal tumor, Yeyuno, Sangrado de tubo digestivo de origen oscuro
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