descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2020 English Publisher:Elsevier BVJournal:Cell Reports, volume 30, pages 599-601 (issn: 2211-1247,

Authors: Amaia Martinez-Usatorre; Michele De Palma;

doi: 10.1016/j.celrep.2020.01.027

pmid: 31968238

A LIGHTning Strike to the Metastatic Niche

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Abstract

Tumor-induced vascular alterations in distant organs have been linked to the spreading of cancer. In this issue of Cell Reports, He et al. (2019) show that targeting the cytokine LIGHT to the pulmonary vasculature prevents the establishment of lung metastasis in mice.

Related Organizations

École Polytechnique Fédérale de Lausanne EPFL
Switzerland

Keywords

Male, Mice, Lung Neoplasms, QH301-705.5, Animals, Lightning Injuries, Immunotherapy, Biology (General), Lung

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