
Ferroptosis is a regulated form of cell death that occurs when phospholipids with polyunsaturated fatty acyl tails are oxidized in an iron-dependent manner. Research in recent years has uncovered complex cellular networks that induce and suppress lethal lipid peroxidation. This SnapShot provides an overview of ferroptosis-related pathways, including relevant biomolecules and small-molecule modulators regulating them.
Cell Death, Iron, Ferroptosis, Humans, Lipid Peroxidation, Oxidation-Reduction, Phospholipids
Cell Death, Iron, Ferroptosis, Humans, Lipid Peroxidation, Oxidation-Reduction, Phospholipids
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