The Angiotensin II Type 2 Receptor for Pain Control
Copyright policy )The Angiotensin II Type 2 Receptor for Pain Control
All well-known deleterious effects of angiotensin (Ang) II, including vasoconstriction, inflammation, water and salt retention, and vascular remodeling, are mediated via its type 1 (AT1) receptor. This explains why AT1 receptor blockers (ARBs) and inhibitors of Ang II synthesis, such as ACE inhibitors and renin inhibitors, are beneficial for cardiovascular disease. Yet, Ang II has a second receptor, the Ang II type 2 (AT2) receptor, the function of which, even after over 20 years of research, remains largely unknown. In this issue, Marion et al. provide a new chapter to the AT2 receptor story.
- Imperial College London United Kingdom
- Erasmus University Medical Center Netherlands
- Erasmus University Rotterdam Netherlands
Angiotensins, Mycobacterium ulcerans, Biochemistry, Genetics and Molecular Biology(all), SDG 3 - Good Health and Well-being, Animals, Humans, Macrolides, Buruli Ulcer, EMC COEUR-09
Angiotensins, Mycobacterium ulcerans, Biochemistry, Genetics and Molecular Biology(all), SDG 3 - Good Health and Well-being, Animals, Humans, Macrolides, Buruli Ulcer, EMC COEUR-09
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