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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao https://doi.org/10.1...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
https://doi.org/10.1016/b978-0...
Part of book or chapter of book . 2019 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Hal-Diderot
Part of book or chapter of book . 2018
Data sources: Hal-Diderot
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Serotonin receptor imaging by 18F-PET

Authors: Billard, Thierry; Liger, François; Verdurand, Mathieu;

Serotonin receptor imaging by 18F-PET

Abstract

Abstract The serotonergic system plays a key modulatory role in the brain. This system is critical in many drug developments for brain disorders via interactions with the 14 subtypes of 5-HT receptors or through reuptake blockade. Positron emission tomography (PET) is an efficient tool for in vivo studies of physiological and pathological processes. Because of its pertinent radiochemical properties, fluorine-18 is one of the most used radioisotopes in PET imaging. This chapter will propose an overview of the 18F-radioligands targeting serotonin receptors, which have been developed over the last few years. Both radiosyntheses and pharmacological properties of these radiotracers will be described, with a specific emphasis on their potential medical applications.

Country
France
Related Organizations
Subjects by Vocabulary

Microsoft Academic Graph classification: medicine.diagnostic_test business.industry Pet imaging Serotonergic Blockade Reuptake Positron emission tomography medicine business Receptor Neuroscience 5-HT receptor

Keywords

[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging, [SDV.IB.MN]Life Sciences [q-bio]/Bioengineering/Nuclear medicine, [CHIM]Chemical Sciences

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  • citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    2
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Average
Average
Average
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