descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1957 English Publisher:Elsevier BVJournal:Archives of Biochemistry and Biophysics, volume 71, pages 358-366 (issn: 0003-9861,

Authors: George Bosworth Brown; M. Earl Balis; Henry Nathan; Daniel H. Levin; Gertrude B. Elion; George H. Hitchings;

doi: 10.1016/0003-9861(57)90046-2

pmid: 13471038

The effects of 6-mercaptopurine on Lactobacillus casei

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Abstract

Abstract The inhibitory action of 6-mercaptopurine has been shown to be manifested by an interference with purine interconversion. The incorporation of adenine and of adenylic acid are affected in different ways by 6-mercaptopurine. These facts have been fitted to a schematic representation of a purine interconversion cycle compatible with the known metabolic behavior of L. casei.

Related Organizations

Kettering University
United States
Cornell University
United States

Keywords

Lactobacillus, Lacticaseibacillus casei, Biochemical Phenomena, Mercaptopurine, Purines, Metabolic Networks and Pathways

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