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Analytical Biochemistry
Article . 1990 . Peer-reviewed
License: CC BY NC ND
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Analytical Biochemistry
Article . 1990
Data sources: Europe PubMed Central
Analytical Biochemistry
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Purification of gramicidin A

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1990 English Publisher:Elsevier BVJournal:Analytical Biochemistry, volume 184, pages 100-103 (issn: 0003-2697, Copyright policy )
Authors: Stuart L. Schreiber; José M. Delfino; Charles J. Stankovic;

doi: 10.1016/0003-2697(90)90019-6

pmid: 1690956

Purification of gramicidin A

Abstract

A simple chromatographic purification of the naturally occurring ion channel-forming pentadecapeptide gramicidin A (gA) is presented. This procedure allows gA to be isolated in gram quantities from the commercially available mixture of isomers after chromatography on silica gel. The gramicidin A obtained in this manner is greater than 95% pure as determined by 1HNMR, HPLC, and amino acid analysis.

Related Organizations
Keywords

Chromatography, Chemistry, Organic, Gramicidin, Silica Gel, Silicon Dioxide

  • BIP!
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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 25
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
25
Average
Top 10%
Average
hybrid