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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Annals of Nuclear Me...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Annals of Nuclear Medicine
Article . 1995 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
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Parametric imaging in nuclear medicine

Authors: N A, Lassen; H, Iida; I, Kanno;

Parametric imaging in nuclear medicine

Abstract

EMISSION TOMOGRAPHY by PET or SPECT allows after certain corrections, to calculate the isotope concentration in the tissue. However, if one wants to image the underlying physiological parameter that the tracer is designed to trace, then these concentration images must be transformed pixel-by-pixel, using appropriate tracer kinetic models. These transformed images are called Parametric Images. They are scaled in the relative units or absolute units pertaining to the parameter imaged, conventionally mi/100 g/min for blood flow, ml/100 g for distribution volume and nM/litre for receptor density to give some specific examples. The text gives a brief review of parametric imaging. The basic tool is the convolution integral. It was introduced for tracer kinetic analysis by Seymour S. Kety in 1951,' and soon after applied by his group for processing autoradiographic images of brain slices to calculate cerebral blood flow in ml/100 g/min' - . The first sections explain the convolution integral and the basic equation of Kety for readers having elementary knowledge of calculus.

Keywords

Tomography, Emission-Computed, Single-Photon, Image Processing, Computer-Assisted, Animals, Humans, Nuclear Medicine, Models, Biological, Mathematics, Tomography, Emission-Computed

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Average
Average
Average
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